Tag Archive for: Public Health

How COVID-19 Causes Loss of Smell

How COVID-19 Causes Loss of Smell - علت کاهش بویایی در جریان بیماری کرونا مشخص شد؟

This article is part of Harvard Medical School’s continuing coverage of medicine, biomedical research, medical education and policy related to the SARS-CoV-2 pandemic and the disease COVID-19.

Temporary loss of smell, or anosmia, is the main neurological symptom and one of the earliest and most commonly reported indicators of COVID-19. Studies suggest it better predicts the disease than other well-known symptoms such as fever and cough, but the underlying mechanisms for loss of smell in patients with COVID-19 have been unclear.

Now, an international team of researchers led by neuroscientists at Harvard Medical School has identified the olfactory cell types in the upper nasal cavity most vulnerable to infection by SARS-CoV-2, the virus that causes COVID-19.

Surprisingly, sensory neurons that detect and transmit the sense of smell to the brain are not among the vulnerable cell types.

Release date: 24 July 2020

Source: Harvard Medical School

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SARS-CoV-2 viral load peaks in the early stages of disease

SARS-CoV-2 viral load peaks in the early stages of disease - بر خلاف انتظار بیشترین بار ویروس کرونا در مراحل ابتدایی و کم علامت ابتلا به بیماری است

Less symptomatic patients have a higher viral load when diagnosed and may carry a higher virus shedding risk potential, possibly representing an important overlooked population for infection containment, report scientists in The American Journal of Pathology.

In a retrospective study, investigators from New York University Langone Health found that the quantity of SARS-CoV-2 (viral load) collected from patients in the emergency department is significantly higher in patients with fewer or milder symptoms who did not require hospitalization—the opposite of what might be expected. Reporting in The American Journal of Pathology, published by Elsevier, they also found that a patient’s history of cancer and cardiovascular disease is associated with higher viral loads even after adjusting for age.

The study was designed to determine possible associations between the viral load measured in patients positive for SARS-CoV-2 and their clinical parameters including severity of symptoms, hospital admission vs direct discharge, length of hospitalization, admission to the intensive care unit, length of need for oxygen support, and overall survival.

Release date: 14 July 2020

Source: Elsevier

COVID-19 outbreak lasts days longer for each day’s delay in social distancing

COVID-19 delayed implementing social distancing - تاخیر در فاصله گذاری اجتماعی در زمان همه گیری کرونا

Epidemiological researchers have published research finding every day a city delayed implementing social distancing measures after the appearance of a first case added 2.4 days to the length of the outbreak.

Release date: 1 June 2020

Source: University of Texas at Austin

COVID-19 may be less common in children

COVID-19 children - کودکان ویروس کرونا

The virus that causes COVID-19 uses a receptor known as ACE2, found on the surface of certain cells in the human body, to enter its victims. Now, Mount Sinai researchers have found that children have lower levels of ACE2 gene expression than adults, which may explain children’s lower risk of COVID-19 infection and mortality. Gene expression is a measure of how much a gene is transcribed.

Release date: 22 May 2020

Source: Mount Sinai School of Medicine

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No evidence of benefit for chloroquine and hydroxychloroquine in COVID-19 patients

No evidence of benefit for chloroquine and hydroxychloroquine in COVID-19 - کلروکین و هیدروکسی کلروکین در درمان کرونا

A large observational study suggests that treatment with the antimalarial drug chloroquine or its analogue hydroxychloroquine (taken with or without the antibiotics azithromycin or clarithromycin) offers no benefit for patients with COVID-19. The study analyzed data from nearly 15,000 patients with COVID-19 receiving a combination of any of the four drug regimens and 81,000 controls.

Release date: 22 May 2020

Source: The Lancet

Patient’s own cells to treat Parkinson’s disease

cells to treat Parkinson - درمان پارکینسون با سلول های پوست

Reprogramming a patient’s own skin cells to replace cells in the brain that are progressively lost during Parkinson’s disease (PD) has been shown to be technically feasible, reports a team of investigators from McLean Hospital and Massachusetts General Hospital (MGH) in the most recent issue of the New England Journal of Medicine.

Release date: 13 May 2020

Source: McLean Hospital

COVID19’s dangerous cardiovascular complications

کووید19 و سکته - COVID19 and strok

COVID-19 can cause serious cardiovascular complications including heart failure, heart attacks and blood clots that can lead to strokes, emergency medicine doctors report in a new scientific paper. They also caution that COVID-19 treatments can interact with medicines used to manage patients’ existing cardiovascular conditions.

Release date: 15 May 2020

Source: University of Virginia

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Exercise: From Birth to Death

Exercise From Birth to Death

Participating in organized sports during childhood and adolescence is associated with greater whole body and leg bone mineral content at 20 years of age, a new study led by Curtin University researchers finds.

Tag Archive for: Public Health

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Electrodiagnostic Medicine

Medical test used for diagnosis different diseases including (but not limited to) radiculopathies, Lower motor neuron disease such as amyotrophic lateral sclerosis, lumbosacral or brachial plexus lesions, polyneuropathies, entrapment neuropathies such as carpal tunnel syndrome, neuromuscular junction disorders such as myasthenia gravis and myopathies. KnowMore…

Pain Medicine

Examples: Neck or back pain, other joint involvement including shoulder & knee pain, pelvic pain, Palliative care. KnowMore…

Specialized Rehabilitation

Including: Cardiac & pulmonary rehabilitation, post-operative care, sport injuries, Pediatric developmental and functional disorders (cerebral palsy, muscular dystrophy, spina bifida), Burns, Geriatrics, cancer. ShowMore…