vaccine Archives - Dr Amin Azhari - دکتر امین اظهری

COVID-19 Nasal Vaccine Candidate Effective At Preventing Disease Transmission

IN THROUGH THE NOSE…

Breathe in, breathe out. That’s how easy it is for SARS-CoV-2, the virus that causes COVID-19, to enter your nose. And though remarkable progress has been made in developing intramuscular vaccines against SARS-CoV- 2, such as the readily available Pfizer, Moderna and Johnson & Johnson vaccines, nothing yet – like a nasal vaccine – has been approved to provide mucosal immunity in the nose, the first barrier against the virus before it travels down to the lungs. But now, we’re one step closer.

Navin Varadarajan, M.D. Anderson Professor of Chemical and Biomolecular Engineering at the Cullen College of Engineering, and his colleagues are reporting in iScience the development of an intranasal subunit vaccine that provides durable local immunity against inhaled pathogens.

Release date: 15 September 2021
Source: University of Houston

what you say in the first minute after a vaccine can be key in reducing a child’s future distress

As we look forward to a fall with hopefully one of the most important vaccination uptakes of children in a generation, a new study provides insights to help parents with reducing post-vaccination distress in younger kids. The study, published in Pain, looked at preschool children who were at least four-to-five years old and what their parents said that could help reduce distress during their vaccination. This study is part of the largest study in the world looking at caregivers and children during vaccinations from birth to the age of five — coined the OUCH Cohort. The OUCH Cohort originally followed 760 caregiver-child dyads from three pediatric clinics in the Greater Toronto Area and were observed during vaccinations during the first five years of a child’s life.

Release date: 13 July 2021
Source: York University

Moderna and Pfizer-BioNTech vaccines prime T cells to fight SARS-CoV-2 variants

Researchers at La Jolla Institute for Immunology (LJI) have found that T cells from people who have recovered from COVID-19 or received the Moderna or Pfizer-BioNTech vaccines are still able to recognize several concerning SARS-CoV-2 variants.

Their new study, published in Cell Reports Medicine, shows that both CD4+ “helper” T cells and CD8+ “killer” T cells can still recognize mutated forms of the virus. This reactivity is key to the body’s complex immune response to the virus, which allows the body to kill infected cells and stop severe infections.

Release date: 01 July 2021
Source: La Jolla Institute for Immunology

Covid-19, Covid-19, Covid-19, Public Health

Prioritizing oldest for COVID-19 vaccines saves more lives, years of life

Challenging the idea that older people with shorter life expectancies should rank lower in coronavirus immunization efforts, new UC Berkeley research shows that giving vaccine priority to those most at risk of dying from COVID-19 will save the maximum number of lives, and their potential or future years of life. Since older age is accompanied by falling life expectancy, it is widely assumed that means we’re saving fewer years of life.

The findings, published in the journal Proceedings of the National Academy of Sciences.

Release date: 25 February 2021
Source: University of California – Berkeley

Covid-19

Concern about loved ones might motivate people to mask up, get vaccine

While many people have listened to messaging about wearing a mask and following social distancing guidelines to limit the spread of COVID-19, resistance remains.

A new study finds that appealing to people’s concerns for their loved ones could overcome this resistance. And it may have implications for encouraging people to mask up and get the new vaccine.

In a recent survey, people who said social distancing and COVID-safety guidelines violated their personal freedoms responded more positively to these ideas when they felt a loved one might be at risk of severe illness for COVID-19.

An and colleagues surveyed 1,074 people across the United States about their attitudes toward the coronavirus. They discovered two distinct sets of attitudes toward social distancing:

Positive beliefs that largely mirror public health messaging
Negative beliefs, including the idea that social distancing violates individual rights and freedoms

Concern about a loved one’s risk of severe COVID-19 infection was tied to both higher positive attitudes and lower negative attitudes toward social distancing. When people considered their own personal risk, they had higher positive attitudes but it did not impact their negative attitudes.

Release date: 18 December 2020
Source: Michigan Medicine – University of Michigan

Geriatrics, Neurologic disorders

Taking steps toward stroke vaccine

New study in mice demonstrates the potentials to prevent post-stroke blood clot for more than two months with a new experimental vaccine (S100A9) provided by Japanese researchers. (American Heart Association)

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