Scientists identify promising new ALS drug candidates

Scientists have taken a significant step forward in the search to find effective new drug candidates for the treatment of motor neurone disease.

Researchers from the Universities of Liverpool (UK) and Nagoya (Japan) have shown that a Selenium-based drug-molecule called ebselen and a number of other novel compounds developed at Liverpool can change many of the toxic characteristics of a protein, superoxide dismutase (SOD1), which causes some cases of Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease.

The study is published in the journal EBioMedicine.

Release date: 1 September 2020