Insomnia identified as a new risk factor for type 2 diabetes

Insomnia identified as a new risk factor for type 2 - بی خوابی خطر ابتلا به دیابت را افزایش می دهد
A new ‘global atlas’ study published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) is the first to identify insomnia as a risk factor associated with increased risk of developing type 2 diabetes (T2D). The study identifies 34 risk factors that are thought to increase (19) or decrease risk (15), as well as a further 21 ‘suggestive’ risk factors where evidence was not quite as strong.
Release date: 8 September 2020

New approach against Parkinson’s disease through stem cell

New approach against Parkinson’s disease through stem cell research - سلول های بنیادی به کمک درمان پارکینسون می آیند
The Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg, experimented on patient-based cell cultures in the laboratory. The new combination of active substances they identified will have to undergo clinical trials before they can be used to treat patients. The research team published its results today in the prestigious scientific journal Science Translational Medicine.
Release date: 10 September 2020

Fatter legs linked to reduced risk of high blood pressure

Fatter legs linked to reduced risk of high blood pressure - چاقی پا یک فاکتور محافظت کننده در برابر فشار خون بالاست
Adults with a higher percentage of fat tissue in their legs were less likely than those with a lower percentage to have high blood pressure.
Research findings held true even after adjusting for age, sex, race and ethnicity, education, smoking, alcohol use, cholesterol levels and waist fat, although to a lesser degree.
Researchers speculate that this protection offered by a higher percentage of leg fat could help identify those at low risk of high blood pressure, or alternatively serve as a target for prevention efforts, although more studies are needed.
Release date: 10 September 2020
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Impact of ACE-i and ARBs for patients with COVID-19

Impact of ACE-i and ARBs for patients with COVID-19 - تاثیر داروهای ضدفشارخون بر کووید19
Low blood pressure, or hypotension, in COVID-19 patients with a history of hypertension appears to be a risk factor for kidney damage and death.
Reducing hypertension medications if and when COVID-19 patients become hypotensive could prevent acute kidney injury and death, according to a new study.
COVID-19 patients previously taking the blood pressure-lowering drugs angiotensin-converting enzyme inhibitors (ACE-i) and angiotensin receptor blockers (ARBs) are more likely to die than those who were not taking the medications.
It is important to note that patients taking ACE-i and/or ARBs may have more advanced cardiovascular disease or other chronic health conditions that further increase the risk for serious complications of COVID-19.
Release date: 10 September 2020

Source: American Heart Association

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Stronger bones thanks to heat and microbiota

Stronger bones thanks to heat and microbiota - تاثیر آب و هوا بر پوکی استخوان
Osteoporosis, a bone disease linked to ageing, is characterised by a loss of bone density, micro-architectural deterioration of the bones and an increased risk of fractures. With one third of postmenopausal women affected, it is a major public health problem. Through epidemiological analyses, laboratory experiments and state-of-the-art metagenomic and metabolomics tools, a research team has observed that exposure to warmer ambient temperatures (34 °C) increases bone strength, while preventing the loss of bone density typical of osteoporosis. Moreover, this phenomenon, linked to a change in the composition of gut microbiota triggered by heat, could be replicated by transplanting the microbiota of mice living in a warm environment to mice suffering from osteoporosis. Indeed, after the transplant, their bones were stronger and denser. These results, to be discovered in Cell Metabolism, make it possible to imagine effective and innovative interventions for prevention and treatment of osteoporosis.
Release date: 10 September 2020

Source: Université de Genève

Mediterranean diet and risk of rheumatoid arthritis

Mediterranean diet and risk of rheumatoid arthritis - تغذیه مناسب برای بیماران روماتیسمی
The Mediterranean diet (MD) has been reported to be associated with significant reduction of non‐communicable diseases. They aimed to assess the relationship between adherence to the MD and the risk of rheumatoid arthritis, especially in high‐risk individuals.

Their results suggest that adherence to the MD could reduce the high risk of RA among ever‐smoking women.

Release date: 9 September 2020

Source: Wiley

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Substance use disorders linked to COVID-19 susceptibility

Substance use disorders linked to COVID-19 susceptibility -مصرف مواد مخدر خطر ابتلا به کرونا را افزایش می دهد

NIH research finds higher risk and worse outcomes for those with addiction.

A National Institutes of Health-funded study found that people with substance use disorders (SUDs) are more susceptible to COVID-19 and its complications. The research, published today in Molecular Psychiatry.

Release date: 14 September 2020

Source: NIH/National Institute on Drug Abuse

Levodopa may improve vision in patients with macular degeneration

Levodopa may improve vision in patients with macular degeneration - داروی پارکینسون ممکن است برای بینایی سالمند مفید باشد

The widely used and well-tolerated drug commonly used to treat Parkinson’s disease may help significantly reduce the need for more costly, more invasive treatments, report investigators in The American Journal of Medicine.

Investigators have determined that treating patients with an advanced form of age-related macular degeneration (AMD) with levodopa, a safe and readily available drug commonly used to treat Parkinson’s disease, stabilized and improved their vision. It reduced the number of treatments necessary to maintain vision, and as such, will potentially reduce the burden of treating the disease, financially and otherwise.

Release date: 10 September 2020

Source: Elsevier

A pain reliever that alters perceptions of risk

A pain reliever that alters perceptions of risk - مسکنی که خطرپذیری افراد را افزایش می دهد

People who took acetaminophen rated activities like “bungee jumping off a tall bridge” and “speaking your mind about an unpopular issue in a meeting at work” as less risky than people who took a placebo, researchers found.

Use of the drug also led people to take more risks in an experiment where they could earn rewards by inflating a virtual balloon on a computer: Sometimes they went too far and the balloon popped.

The study was published online in the journal Social Cognitive and Affective Neuroscience.

Release date: 8 September 2020

Source: Ohio State University

Obesity may alter immune system response to COVID-19

Obesity may alter immune system response to COVID-19 - چاقی باعث بروز تغییراتی در ایمنی علیه کرونا می شود.

Obesity may cause a hyperactive immune system response to COVID-19 infection that makes it difficult to fight off the virus, according to a new manuscript published in the Endocrine Society’s journal, Endocrinology.

Release date: 3 September 2020

Source: The Endocrine Society